The relationship between sleep-wake cycle and cognitive functioning in young people with affective disorders

JS Carpenter; R Robillard; RSC Lee; DF Hermens; SL Naismith; D White; B Whitwell; EM Scott; IB Hickie

Journal article

The relationship between sleep-wake cycle and cognitive functioning in young people with affective disorders

JS Carpenter, R Robillard, RSC Lee, DF Hermens, SL Naismith, D White, B Whitwell, EM Scott, IB Hickie

Plos One | PUBLIC LIBRARY SCIENCE | Published : 2015

DOI: 10.1371/journal.pone.0124710

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Abstract

Although early-stage affective disorders are associated with both cognitive dysfunction and sleep-wake disruptions, relationships between these factors have not been specifically examined in young adults. Sleep and circadian rhythm disturbances in those with affective disorders are considerably heterogeneous, and may not relate to cognitive dysfunction in a simple linear fashion. This study aimed to characterise profiles of sleep and circadian disturbance in young people with affective disorders and examine associations between these profiles and cognitive performance. Actigraphy monitoring was completed in 152 young people (16-30 years; 66% female) with primary diagnoses of affective disord..

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University of Melbourne Researchers

Rico Lee Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

IBH was funded by a National Health and Medical Research Council Program Grant (No. 566529) and Australian Fellowship (No. 464914). DFH was supported by a grant from NSW Health Mental Health and Drug & Alcohol Office. SLN was funded by a National Health and Medical Research Council Clinical Development Award (No. 1008117). RR received a postdoctoral training award from the Fonds de la recherche en sante du Quebec. RSCL and JSC were supported by the NHMRC Centre of Research Excellence in Optimising Early Interventions for Young People with Emerging Mood Disorders (No. 1061043). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.